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Mary L.  Schneider, Ph.D., OTR

 

Professor of Kinesiology and Psychology, Program Director
2175 Medical Sciences Center
1300 University Avenue
Madison, WI  53706

Main: 608-265-5118

schneider@education.wisc.edu

Education and Training

Ph.D.
Psychology
University of Wisconsin-Madison
M.S.
Psychology
University of Wisconsin-Madison
B.S.
Occupational Therapy
University of Wisconsin-Madison

Practice and Experience

My clinical work has been primarily with children with attention deficit hyperactivity disorders, autism, and other pediatric psychiatric diagnoses. My focus has been on how sensory processing deficits affect successful occupation.

Research Interests

In my work I use a primate model to study the effects of maternal alcohol consumption alone, or in combination with maternal stress, on offsprings behavior and physiology. I examine the timing of the exposure for temporal windows of vulnerability. I also study sensory processing disorders in a monkey model, to increase our understanding of the etiology and underlying physiology of the disorder. Positron emission tomography (PET), prepulse inhibition sensorimotor gating), and behavioral observations are used to accomplish this aim.

Intra and Extramural Funding

National Institute of Alcohol Abuse and Alcoholism
6/01/06 - 5/31/11
Principal Investigator, Fetal alcohol effects in monkeys: Dopamine and behavior AA12277.
This project will assess dopamine receptor binding, DA transporters and cerebral FDG metabolism after cognitive testing in several brain regions using positron emission tomography (PET) in monkeys from prenatal-stressed and/or fetal alcohol-exposed pregnancies.

National Institute of Alcohol Abuse and Alcoholism
08/01/06 - 07/31/11
Principal Investigator, Moderate Level Prenatal Alcohol Exposure in Primates AA10079.
This project examines the effects of gestational timing of maternal alcohol consumption on neurotransmitter function using PET neuroimaging. We will also study sensory processing and prepulse inhibitions in these monkeys to examine underlying neurobiology of sensory processing disorder. We will also assess whether prenatal alcohol-exposed monkeys are more vulnerable to excessive alcohol comsumption in adulthood and whether the timing of the prenatal alcohol exposure affects adult drinking patterns.

Teaching Areas

I teach courses related to pediatric occupational therapy theory and practice.

Publications

Schneider, M.L., Moore, C.F., Gajewski, L. L., Larson, J.A., Roberts, A. D., Converse, A.K., DeJesus, O.T. (2008). Sensory processing disorder in a primate model: Evidence from a longitudinal study of prenatal alcohol and prenatal stress effects. Child Development, 79(1), 100-113.
Kraemer, G.W., Moore, C.F., Newman, T.K., Barr, C.S., Schneider, M.L. (2008).
Moderate level fetal alcohol exposure and serotonin transporter gene promoter polymorphism affect neonatal temperament and LHPA axis regulation in monkeys. Biological Psychiatry,63, 317-324.
Schneider, M.L., Moore, C.F., DeJesus, O.T., Converse, A.K. (2008).
Prenatal stress influences on neurobehavior, stress reactivity, and dopaminergic function in rhesus macaques. In T. Burbacher, G.P. Sachett, & K.S. Grant (Eds.) Primate Models of Children's Health and Developmental Disabilities (pp. 213-258).New York: Elsevier, Inc.
Schneider, M.L., Moore, C.F., Gajewski, L., Laughlin, N., Larson, J., Gay, C., Roberts, A., Converse, A., DeJesus, O.T. (2007). Sensory processing disorder in a nonhuman primate model: Evidence for occupational therapy practice. American Journal of Occupational Therapy.61, 247-253.
Moore, C.F., & Schneider, M.L. (2006). Prenatal development. In N.J. Salkind (Ed.), Encyclopedia of Human Development, pp. 1018-1020. Thousand Oaks, CA: Sage.
Schneider, M.L., Champoux, M. & Moore, C.F. (2006). Neurobehavioral assessment of nonhuman primate neonates. In G.P. Sackett, G.C. Ruppenthal, & K. Elias (Eds.), Nursery Rearing of Nonhuman Primates in the 21st Century (pp. 215-247). Springer Science-Business Media, Inc., New York.
Schneider ML, Moore CF, Barnhart TE, Larson JA, DeJesus OT, Mukherjee J, Nickles JR, Converse AK, Roberts AD, Kraemer GW (2005). Moderate level prenatal alcohol exposure alters striatal dopamine system function in rhesus monkeys. Alcoholism: Clinical and Experimental Research, 29(9), 1685-1697.
Roberts, A. D., Moore, C. F., DeJesus, O. T., Barnhart, T. E., Larson, J. A., Mukherjee, J., Schneider, M.L. (2004). Prenatal stress, moderate fetal alcohol, and dopamine system function in rhesus monkeys. Neurotoxicology and Teratology, 26, 169-178.
Schneider, M. L., Moore, C. F., & Kraemer, G. W. (2004).
Moderate level alcohol during pregnancy, prenatal stress, or both and limbic-hypothalamic-pituitary-adrenocortical axis response to stress in rhesus monkeys. Child Development, 75(1), 96-109.
Schneider, M.L., Moore, C.F. (2003).
On the relevance of prenatal stress to developmental psychopathology. A primate model. In D. Cicchetti (Ed.) Neurodevelopmental mechanisms in psychopathology. (pp. 155-186) Cambridge University Press.
Schneider, M.L., Moore, C.F., Kraemer, G.W., Roberts, A.D., DeJesus, O.T. (2002).
The impact of prenatal stress, fetal alcohol exposure, or both on development: Perspectives from a primate model. Journal of Psychoneuroendocrinology, 27, 285-298.
Jacobs, S. E., & Schneider, M. L. (2001).
Neuroplasticity, and the Environment: Implications for sensory integration. In S Smith, E. Blanch & R Schaaf (Eds.) Understanding the nature of sensory integration with diverse populations (pp. 29-42). Therapy Skill Builders.
Schneider, M.L., Moore, C. Kraemer, G.W. (2001)
Moderate alcohol during pregnancy: Learning and Behavior in adolescent rhesus monkeys. Alcoholism: Clinical and Experimental Research, 25 (9), 1383-1392.
Schneider, M.L., Moore, CL, & Becker, EF (2001).
Timing of moderate alcohol exposure during pregnancy and neonatal outcome in rhesus monkeys (Macaca mulatta), Alcoholism: Clinical and Experimental Research, 25, 1238 -1246.
Schneider, M. L., Moore, C.F., Roberts, A.D., & DeJesus, O.T. (2001).
Prenatal stress alters early neurobehavior, stress reactivity and learning in nonhuman primates: A brief review. Stress, 4, 183-193.
Schneider, M. L. & Moore, C.F. (2000).
Effect of prenatal stress on development: A nonhuman primate model. The Minnesota Symposia on Child Psychology (pp.201-243), Lawrence Erlbaum, New Jersey.
Schneider, M. L., Roughton, E. C., Koehler, A. J. & Lubach, G. R. (1999).
Growth and Development Following Prenatal Stress Exposure in Primates: An Examination of Ontogenetic Vulnerability. Child Development, Volume 70, Number 2, 263-274.
Roughton, E. C., Schneider, M. L., Bromley, L., & Coe, C. L. (1998).
Maternal endocrine activation during pregnancy alters neurobehavioral state in primate infants. American Occupational Therapy Journal, 52, 90 - 98.
Schneider, M. L., Roughton, E.C., & Lubach, G. (1997).
Moderate alcohol consumption and psychological stress during pregnancy induces attention and neuromotor impairments in primate infants. Child Development, 68 (5), 747-759.
Schneider, M. L., & Suomi, S.J. (1992).
Neurobehavioral assessment in rhesus monkey neonates (Macaca mulatta): Developmental changes, behavioral stability, and early experience. Infant Behavior and Development, 15 (2), 155-177.