Kinesiology Research Projects Supported by Federal Grants

• Lisa Colbert. NIH, R21, 9/15/06-8/31/09, Physical Activity Measurement in Older Adults
• The goal of this research is to compare the validity of various methods of measuring physical activity in older adults, comparing pedometry, accelerometry, multiple-sensor units, and surveys to doubly labeled water and metabolic chamber measures of energy expenditure.
• Co-Investigators: Dale Schoeller, UW Dept of Nutritional Sciences; Ann Ward, UW Dept of Kinesiology; KyungMann Kim, UW Biostatistics.
• Dane Cook. NIH, R01, 9/16/05-6/30/10, Imaging the Cognitive Modulation of Pain in Fibromyalgia
  • Specific aims are to determine the psychophysical and neural aspects of pain modulation in fibromyalgia and test whether central nervous system modulation of pain is impaired in unexplained pain (FM) versus both an explained pain group (rheumatoid arthritis patients) and healthy controls.
  • Co-Investigators: Richard Davidson (Director, Waisman Laboratory for Brain Imaging and behavior), Dan Muller (Rheumatology) and Andrew Alexander (Medical Physics)
• Dane Cook. Veterans Affairs, 10/01/08 – 9/30/2012, Imaging pain modulation in Gulf War veterans with chronic muscle pain
• Specific aims are to determine the psychophysical and neural aspects of pain modulation in GVs with chronic muscle pain (CMP) and test whether central
• Co-Investigators: Alan Bridges (Chief-of-staff, VA Madison), Sterling Johnson (School of Medicine and Public Health) & Andrew Alexander (Medical Physics)
• Dorothy Edward. NIH Sub-Award from Georgetown University, Patient Recruitment Retention, Intervention and Outcome (PRRIO)
  • The purpose of this study is to examine the attitudinal and environmental barriers to exercise in middle aged women with first clinical stroke.
• Andrea Mason. NSF, 2/28/04-2/28/10, Career: Sensory Information For Interaction in Single User and Collaborative Environments
  • The purpose of this research is to understand how sensory feedback conditions in virtual environments affect the planning and performance of simple and collaborative object manipulation.  Specifically we are investigating what sensory (graphic and haptic) information users require to move effectively in computer-generated environments, when that information is required, and how best to present the information so that it can be effectively used. 
• Mary Schneider. NIH, R01, 6/1/06-5/31/11, Fetal Alcohol Effects in Monkeys: Dopamine and Behavior
  • The goal of this research is to assess whether moderate prenatal alcohol exposure and/or prenatal stress alters dopamine receptor and transporter binding in the brain using PET neuroimaging, cognitive performance dependent on DA function, cerebral glucose metabolism during executive function task, and pre-pulse inhibition (sensorimotor gating) in a rhesus monkey model.                
• Mary Schneider. NIH, R01, 8/1/06-7/31/11, Moderate Level Prenatal Alcohol Exposure in Primates
• The aims of this research are to assess whether the timing of prenatal alcohol exposure alters dopaminergic function, pre-pulse inhibition (sensorimotor gating) and risk for excessive alcohol consumption during adulthood.  Effects of alcohol consumption on neuroreceptor and transporter dopaminergic function are assessed using PET neuroimaging   technologies. A rhesus monkey model is employed.
• Co-Investigators: Colleen Moore (Psychology),James E Holden, Alexander Converse, Onofre DeJesus, Robert Nickles (Medical Physics). Bradley Christian (Psychiatry and Medical Physics)
• Bill Schrage. NIH, R21, 4/01/09-3/31/11, Aging and Microvascular Dysfuntion in Human Skeletal Muscle. (Pending, 8.2 percentile)
  • The goal is to compare anti-oxidant and pro-oxidant enzyme systems in aging resistance vessels and muscle fibers, and their determine the collective impact on microvascular function in older adults.
• Peter van Kan. NIH, R01, 12/1/02-5/30/09, Function of Magnocellular Red Nucleus in Reach-To-Grasp (Martha McCurdy, Co-Investigator)
  • This project aims to elucidate the role of the primate magnocellular red nucleus in sensorimotor integration, specifically with regards to whether red nucleus neurons encode muscle activation patterns or kinematic parameters.

Kinesiology Faculty Collaborated Federal Research Projects

• David Gustafson, NIH, P50, 9/30/08-8/31/13, Using Technology to Enhance Cancer Communication and Improve Clinical Outcomes
• This project is investigating the problems associated with cancer communication in a rapidly changing communication environment.
• Co-Investigator: Lisa Colbert

   

• Timothy Baker, NIH, P50, 9/1/04 – 8/30/09, Transdisciplinary Tobacco Use Research Centers (TTURC2) Tobacco Dependence: Treatment and Outcomes.
• Through a transdisciplinary effort, this project aims to continue to create       and foster new and integrative research in tobacco control, to attract outstanding students and scientists to the field of tobacco research, and to train them to become outstanding tobacco scientists.
• Co-Investigator: Lisa Colbert

 

• Pollak, Seth, NIH 2005 - 2010: National Institute of Mental Health: Neurobehavioral Correlates of Early Deprivation. Co-Investigator: Mary Schneider
  • The goals of this R01 project are to characterize the brain-behavior effects on cognition, affective, and sensory-motor processing among severely neglected children who developed within institutionalized settings.

Kinesiology Research Projects Supported by Foundations and Other Sources

• Ruth Benedict. Cerebral Palsy International Research Foundation (CPIRF), Outcomes of interventions for spasticity management among children and young adults with cerebral palsy and their caregivers, 1/1/09-12/31/10
• Ruth Benedict. Pedal-with-Pete, Expansion of Outcomes of interventions for spasticity management among children and young adults with cerebral palsy and their caregivers, 1/1/09-12/31/09
• Ronnie Carda. UW Foundation, Physical Education Activity Lecture
  • The fund is used to provide a lecture series honoring the contributions of Julia Brown, the former Coordinator of the PE Activity Program. 
• Ronnie Carda. UW Foundation, Service Learning for the Elderly
  • The fund is to provide a Weight Training course having a service learning component in which students act as fitness instructors/personal trainers for the elderly residents of Oakwood Village to improve strength and muscle fitness.
• Lisa Colbert WARF, 9/15/06-8/31/09Physical Activity Measurement in Older Adults
  • The goal of this research is to compare the validity of various methods of measuring physical activity in older adults, comparing pedometry, accelerometry, multiple-sensor units, and surveys to doubly labeled water and metabolic chamber measures of energy expenditure.
• Dane Cook Virginia Horne Henry, Functional Neuroimaging of Exercise-Induced Modulation of Pain in Women with Fibromyalgia
  •  The primary objective of the proposal is to determine the influence of acute exercise on pain and brain responses in women with fibromyalgia (FM) using functional magnetic resonance imaging (fMRI).
• Dane Cook The Chronic Fatigue and Immune Dysfunction Syndrome (CFIDS) Association of America, Metagenomics approach to study chronic fatigue syndrome patients
  • Specific aims are to: 1) use metagenomics to determine the intestinal microbiota communities in CFS patients and controls and 2) to determine the influence of maximal exercise on gut microbiota translocation into the peripheral blood and its relationship to symptoms of post-exertional malaise.
• Dorothy Farrar-Edwards Virginia Horne Henry, Barriers to Exercise and Physical Activity in Women After Stroke
• Tim Gattenby UW Foundation, Heideman Adapted Fitness Fund
  • To support teaching, research and service activities in Adapted Physical Activity
• Kreg Gruben WARF, Altered directional control of foot force disrupts walking after stroke
  • This project aims to provide direct  empirical evidence that foot force misdirection causes gait difficulties after stroke. 7/08–6/09.
• Kreg Gruben Virginia Horne Henry, Foot Force Direction During Walking in Elderly Women
  • This project aims to describe how aging affects walking ability in women. 5/08–8/09
• Li Li Ji Virginia Horne Henry, Oat Avenanthramide in Physically Active Women: Protection Against Muscle Inflammation (2007-2008)
  • The project is aimed to investigate whether muscle inflammatory damage caused by lengthening contraction can be prevented by oat antioxidants in college-age women
• Li Li Ji Virginia Horne Henry, Oat Supplementation and Exercise Training in the Post-Menopausal Women: Recovery from Myocardial Infarction (2008-2009)
  • The purpose of the study is to examine the effect of oat avenanthramides supplementation on the recovery of post-myocardial infarction patients
• Li Li Ji Virginia Horne Henry, Oat Avenanthramide Supplementation in the  Elderly Women: Protection Against Exercise-Induced Inflammation (2009-2010)
  • To investigate whether dietary supplementation of oat antioxidants protects against exercise-induced inflammatory response in aged women
• Kelli Koltyn Jacobs Institute of Women’s Health, Association Between Physical Activity, Physical Functioning, and Quality of Life in Older Women Residing in Long-Term Care Facilities
  • The purpose of this project is to examine the relationship between pain, physical activity, physical functioning, and quality of life in older women living independently in the community and in assisted-care facilities.
• Kelli Koltyn WARF, Attenuation of Pain in Men and Women: Mechanisms of Exercise-Induced Analgesia
  • The purpose of this study is to examine whether men and women differ in the mechanisms of exercise-induced analgesia.Kelli Koltyn Virginia Horne Henry, Physical Activity Preferences and Barriers in Minority College Students
• Kelli Koltyn, Virginia Horne Henry, Physical Activity Preferences and Barriers in Minority College Students.
  • The purpose of this study is to examine physical activity behavior in a diverse sample of college students including current physical activity levels, preferences toward physical activity, and primary barriers that prevent students from being physically active.
• Cindy Kuhrasch DoIT, Engage Impact Award-
  • Students will use develop a biomechanical analysis on a selected motor skill, combine it with videotaped examples, and combine them to create an educational module.  The educational, interactive module will then be shared with teachers via a website. 
• Elizabeth Larson Virginia Horne Henry, Biomarkers and Activity Patterns of Resilient and Vulnerable Caregivers of Children with Disabilities
  • This project 1) identifies caregivers with genotypes which may be more and less vulnerable to caregiving stress, and 2) examines the psychological well-being and health promoting activity patterns for genetically- vulnerable and resilient caregivers
• Jo-Anne Lazarus Virginia Horne Henry, Assessment of Motor Function of the Upper Limbs in Ecologically Vivid Environments in Women with Parkinson’s Disease
  • The proposed project will examine the kinematics of hand and arm function during activities of daily living in women with Parkinson's disease.  (2008-2009)
• Jo-Anne Lazarus Virginia Horne Henry, Postural Control and Symptom Relief in Women with Parkinson’s Disease: A Study on the Efficacy of Pilates as an Intervention
  • The proposed project will study the efficacy of two different 12-week exercise programs (Pilates, American Parkinson’s Disease Association general exercise program) administered twice weekly as an intervention for ameliorating the symptoms of Parkinson’s disease. (2009-2010)
• Bill Schrage American Heart Association, Neural adrenergic vasoconstriction in exercising females: Impact of hormone status
• Bill Schrage American Federation for Aging Research, Aging and the Red Blood Cell: Linking Endothelial and Exercise Dysfunction
• Bill Schrage Virginia Horne Henry, Neural Control of Blood Flow in Exercising Females: Impact of Hormone Status
• Leslie Vaughan WARF Award, 2009-2010. To study relationships between aging, executive function, and instrumental activities of daily living in older adults who demonstrate a range of cognitive performance.
• Andy Winterstein Virginia Horne Henry, Long Term Outcomes of Knee Injuries in Physically Active Adolescent and Young Adult Females

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